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VariantBaits™遗传性肿瘤46基因捕获试剂盒

检测试剂

产品简介

VariantBaits™遗传性肿瘤46基因捕获试剂盒由11,671条LC Sciences专利技术μParaflo®微流体芯片合成的RNA探针组成, 总捕获目标区域为140.03kb。试剂盒检测包含乳腺癌、卵巢癌相关BRCA1、BRCA2,结直肠癌相关APC、MLH1等11种癌症的46个热点基因,对热点基因进行目标区域捕获,定位癌症的突变情况。

产品信息

癌种列表

探针稳定性

检测流程

订购信息

 

合作成果

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8.Myllykangas S, Buenrostro JD, et al. (2011) Efficient targeted resequencing of human germline and cancer genomes by oligonucleotide-selective sequencing. Nat Biotechnol 29, 1024-27.

9.Diep D, Plongthongkum N, Gore A, Fung H, Shoemaker R, Zhang K. (2012) Library-free methylation sequencing with bisulfite padlock probes. Nature Methods 9(3), 270-2.

10.Labrie V, Buske OJ, Oh E, Jeremian R, Ptak C, Gasiūnas G, Maleckas A, Petereit R, Žvirbliene A, Adamonis K et al.(2016) Lactase nonpersistence is directed by DNA-variation-dependent epigenetic aging. Nature Structural &Molecular Biology 23(6):566-73.

11.Zaccai F, C T, Savitzki D, Zivony-Elboum Y, Vilboux T, Fitts EC, Shoval Y, Kalfon L, Samra N, Keren Z. (2017) Phospholipase A2-activating protein is associated with a novel form of leukoencephalopathy. Brain 140(2), 370-386.


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